Wrist Cartilage - High Resolution in Vivo MR T2 Mapping- a Feasibility Study

Wrist Cartilage - High Resolution in Vivo MR T2 Mapping- a Feasibility Study

Purpose:Evaluate the feasibility of T2 cartilage mapping on MRI of the wrist and correlate with T2 mapping of knee cartilage.

Study protocol: Phase 1. 10 healthy volunteers, Phase 2. 10 volunteers with osteoarthritis of the wrist, Phase 3. 50 patients for studies for routine MR of the wrist.

MRI protocol: 3 T unit((Signa EXITE HDx),T1, T2 and T2 mapping sequences on axial and coronal orientation.

Inclusion Criteria:

• Phase 1. Age:18-40
• Phase 2: No age limit, known OA on pre-existing X-rays
• Phase 3: No age limit, routine MRI of the wrist

Exclusion Criteria:

• Phase 1, 2: wrist trauma/surgery
• All phases: any contraindication for MR: eg metals, claustrophobia, etc.