Labor Analgesia With Ropivacaine and Clonidine

Labor Analgesia With Ropivacaine Added to Clonidine. A Randomized Clinical Trial

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

Inclusion Criteria:

• Singleton healthy
• Full-term pregnancy
• American Society of Anesthesiologists physical status I or II

Exclusion Criteria:

• Patients who had received opioids
• History of hypersensitivity to local anesthetic or to clonidine
• Fetus showed signs of possible intrauterine suffering
• Fetus showed signs of possible neurological deficit