Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor

Impact on Maternal and Fetal Wellbeing and on Labor Curve of Intrathecal Clonidine Addiction for Labor Analgesia. A Randomized Controlled Trial.

The study aims to evaluate the impact of the addition of 20 mcg of intrathecal clonidine in combined spinalepidural for labor analgesia on the local anesthetic consumption, on labor performance and on maternal fetal well-being.

Inclusion Criteria:

• Written maternal informed consent
• Singleton pregnancy
• Gestational age ≥ 37 weeks,
• ASA I
• BMI < 30
• fetus in cephalic presentation

Exclusion Criteria:

• Suspect or certainty of fetal malformation,
• Presence of conditions such as preeclampsia, multiparity, preterm labor
• History of adverse reaction to α-2 adrenergic agonists
• Nicotine addiction
• Chronic use of opioid