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| Name | Class |
|---|---|
| Beijing Obstetrics and Gynecology Hospital | OTHER |
| International Peace Maternity and Child Health Hospital | OTHER |
| Nanjing Medical University | OTHER |
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Women requiring epidural labor analgesia were randomized into two groups, one with the local anesthetic chloroprocaine and the other with ropivacaine. The primary outcome was to observe the analgesic scores of the two groups of drugs as well as adverse reactions.
Mothers who met the study criteria vertebrae were included and then divided into two groups. Labor analgesia was provided by epidural anesthesia with a low concentration of local anesthetic (chloroprocaine or ropivacaine) combined with sufentanil. Data related to labor analgesia such as pain scores, motor tissue scores, and body temperature were collected and statistically analyzed to compare the efficacy and adverse effects of the two local anesthetics and to draw conclusions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chloroprocaine group | Experimental | Selection of local anesthetics for epidural labor analgesia with low concentration of chloroprocaine combined with sufentanil |
|
| Ropivacaine group | Placebo Comparator | Selection of local anesthetics for epidural labor analgesia with low concentration of ropivacaine combined with sufentanil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chloroprocaine | Drug | Selection of low concentration of chloroprocaine as local anesthetic for labor analgesia |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of effective analgesia | Percentage of effective analgesia within 30 min after the first epidural addition at the beginning of labor analgesia in both groups | 30 min after the first epidural addition at the beginning of labor analgesia |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| C004616 | chloroprocaine |
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Anhui Women and Children's Medical Center |
| UNKNOWN |
| Jiaxing Maternity and Child Health Care Hospital | OTHER |
| Gansu Maternal and Child Health Center | UNKNOWN |
| Urumqi Maternal and Child Health Center | UNKNOWN |
| Shengjing Hospital | OTHER |
| Zhongnan Hospital | OTHER |
| Second Affiliated Hospital of Wenzhou Medical University | OTHER |
| Second Hospital of Jilin University | OTHER |
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|
| D000588 |
| Amines |