A Study to Determine the Effectiveness and Tolerability of MK8141 in Patients With High Blood Pressure (MK-8141-006)

A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Study to Assess the Efficacy and Tolerability of MK8141 in Hypertensive Patients

This study will evaluate the effectiveness and tolerability of MK8141 in lowering blood pressure in patients who have hypertension (high blood pressure).

Inclusion Criteria:

• You are 35 to 65 years of age
• In the past 14 days you have not been treated for hypertension
• In the past 14 days you have not taken more than 2 medications to treat high blood pressure
• You are a woman who is not able to have children or do not use birth control

Exclusion Criteria:

• You are taking more than 2 medications to treat high blood pressure
• You have a history of a stroke, transient ischemic attack (TIA), heart attack, congestive heart failure, coronary artery bypass surgery
• You have Type 1 or 2 diabetes mellitus
• You have an active liver disease, gallbladder disease, or bowel disease
• You are HIV positive
• You have certain types of cancer
• You abuse drug or alcohol
• You have participated in another clinical study in last 4 weeks