Safety and Economics of Parenchymal Transection in Minimally Invasive Liver Surgery | NCT07750275

NCT07750275

Overview

NCT ID: NCT07750275
Lead Sponsor: University of MoliseOTHER
Official Title: Safety and Economics of Parenchymal Transection in Minimally Invasive Liver Surgery (LIVER-MIND 2): a Multicentre Retrospective Registry of the Italian Society of Endoscopic Surgery (SICE)
Brief Summary: LIVER-MIND 2 is a multicentre, observational, retrospective registry coordinated by the SICE HPB and Minimally Invasive Surgery Working Group, enrolling consecutive adults undergoing elective minimally invasive (laparoscopic, robotic or hybrid) liver resection between January 2021 and December 2025 across ≥15 high-volume or dedicated centres (target >30 centres).
Conditions: Liver Surgery
MINIMALLY INVASIVE LIVER SURGERY
Liver Neoplasm

Status and Timeline

Status: Enrolling by invitation
Last Update Posted: Aug 6, 2026Actual
Start Date: Jan 1, 2021Actual
Primary Completion Date: Dec 2026Estimated

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Age ≥ 18 years

Elective minimally invasive liver resection

Laparoscopic, robotic or hybrid approach

Benign or malignant disease

Signed informed consent for use of anonymised data

Data completeness ≥ 70% in the CRF

Exclusion Criteria:

Urgent or emergency surgery

Liver transplantation (donor / recipient)

Associated major non-hepatic biliary or vascular resection

Lack of consent or follow-up

Participation in conflicting interventional trials

Surgery before January 2021

Robotic procedures performed during the learning-curve phase (first 65 robotic cases per centre, per Rahimli et al.)

Study Plan

Study Type: Observational
Phase: No data available
Enrollment: 800Estimated
Primary Purpose: No data available
Allocation: No data available
Interventional Model: No data available
Masking

Contacts and Locations

Central Contacts: No data available
Locations: University of Molise

Similar Studies

NCT00553033Unknown status

Laparoscopic Liver Resection

NCT03270917Active, not recruiting

ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection

NCT06770803Not yet recruiting

High Versus Low Pneumoperitoneum PressUre for Parenchymal Transection in Minimally Invasive Major Liver Surgery

NCT07169877Completed

Does a Minimally Invasive Approach to Liver Resection Improve Postoperative Outcomes?

NCT05475054Completed

Impact of Minimally Invasive and Open Liver Surgery in Different BMI-classes

NCT02131441Unknown status

Surgical Specification and Efficacy Evaluation of Total Laparoscopic Left Liver Resection

NCT06594289Recruiting

Evaluation of the Safety and Effectiveness of Pringle Method Combined With IVC Flow Limiting and Blocking Method in Laparoscopic Hepatectomy Based on Non-restrictive Fluid Therapy Strategy

NCT03323242Unknown status

The Use of Technical Vessel Sealing Devices for Recipient Hepatectomy in Liver Transplantation