Mental Rotation and Motor Imagery Training in Multiple Sclerosis | NCT07749690

NCT07749690

Overview

NCT ID: NCT07749690
Lead Sponsor: Abant Izzet Baysal UniversityOTHER
Official Title: Mental Rotation and Motor Imagery Training for Upper-Extremity Function in Relapsing-Remitting Multiple Sclerosis: A Randomized Controlled Trial
Brief Summary: This randomized controlled trial investigated the effects of sequential laterality, motor imagery, and mental rotation training in individuals with relapsing-remitting multiple sclerosis. Both groups received conventional physiotherapy, while the intervention group received structured cognitive-motor training and the control group received active visual-attention training.
Conditions: Relapsing Remitting MS (RRMS)
Interventions

Status and Timeline

Status: Completed
Last Update Posted: Aug 6, 2026Actual
Start Date: Feb 15, 2024Actual
Primary Completion Date: Jan 15, 2026Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Diagnosed with definite relapsing-remitting multiple sclerosis by a neurologist according to the revised McDonald criteria

Not experiencing an acute MS relapse

Mini Mental State Examination score ≥24

No clinical MS relapse within the previous 3 months

No corticosteroid treatment for an MS relapse within the previous 3 months

Expanded Disability Status Scale score between 1.5 and 6.0

Modified Ashworth Scale score ≤2

Sufficient communication ability to understand visual and verbal instructions and follow the training protocol

Able to attend at least 80% of the planned sessions

Able to complete the Movement Imagery Questionnaire-3

Exclusion Criteria:

Any medication change within the previous 3 months

Uncorrected severe visual or hearing impairment

A communication disorder preventing the perception of or response to the visual and verbal stimuli used in the study

Participation in another structured upper-extremity rehabilitation program or interventional study during the study period

Presence of an additional neurological disorder

Advanced sensory loss or proprioceptive impairment that could affect participation in the intervention

Botulinum toxin injection within the previous 3 months

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 54Actual
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking

Contacts and Locations

Central Contacts: No data available
Locations: Abant Izzet Baysal University Faculty of Health Science

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