Inclusion Criteria:

• Left ventricular ejection fraction (LVEF) ≤ 49%;
• Echocardiographic image quality judged to be at least adequate according to a four-point visual image quality scale (good, adequate, poor, or inadequate)

Exclusion Criteria:

• Inability to maintain the correct position for acquiring echocardiographic images;
• Arrhythmias that make multi-beat acquisition impossible (if required), such as frequent extrasystoles (supraventricular or ventricular) and atrial fibrillation;
• Failure to visualize more than 2 segments of the left ventricle (LV), or inability to assess more than 3 segments during 3D GLS analysis;
• Failure to sign the informed consent form and inability of the participant to understand the objectives of the study