Effect of Irrigation of Triamcinolone Versus Hypertonic Saline in Decreasing Seroma Post Abdominoplasty | NCT07733921

NCT07733921

Overview

NCT ID: NCT07733921
Lead Sponsor: Cairo UniversityOTHER
Official Title: Effect of Irrigation of Triamcinolone Versus Hypertonic Saline in Decreasing Seroma Post Abdominoplasty
Brief Summary: A total of 90 abdominoplasty patients were randomly assigned into three groups:

Group A: Triamcinolone group, Group B: Hypertonic saline group, Group C: Control group

Randomization:

It was performed using the closed envelope technique.

Technique:

After performing a Lipo-abdominoplasty Group A (triamcinolone) irrigates 10 cm saline mixed with two 40 mg vials through the umbilicus into dead space; Group B (hypertonic saline) irrigates 20 cm of 10% solution similarly; Group C (control) receives no irrigation
Conditions: Seroma Formation
Interventions

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: Female
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Females

Age: 18-65

BMI ≤ 39

Pendulous abdomen grades 3 and 4 according to the Matarasso classification of 1991.

Exclusion Criteria:

Age: < 18 years and > 65 years

BMI: >39.1

Known allergies to steroidal compounds

Uncontrolled medical comorbidities

open abdominal surgeries other than caesarian sections.

Ventral hernias

Ehlers-Danlos and other hyper elasticity syndromes

Participant Group/Arms

Group A Triamcinolone groupActive Comparator

Irrigation of Triamcinolone post lipo-abdominoplasty 10cc normal saline 0.9% with 80mg of Triamcinolone

Drug: Irrigation of Triamcinolone

Group B Hypertonic salineActive Comparator

Irrigation of Hypertonic Saline post lipo-abdominoplasty 20cc of 10% Hypertonic Saline

Drug: Hypertonic Saline 10%

Group C Control GroupPlacebo Comparator

Lipo-Abdominoplasty

Drug: Control