Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The objective of this prospective randomised clinic study is to investigate the effect of peritoneal cavity saline irrigation during abdominal hysterectomies on postoperative infectious morbidities and gastrointestinal disturbance. The participants will be randomised to either an irrigation of abdominal cavity or the control group after vaginal closure. Assignment to one of the two treatment groups will be determined using a computer generated random numbers. Primary outcome is the rate of postoperative infectious morbidities. Secondary outcome is the rate of gastrointestinal disturbances (nausea, vomiting), use of antiemetic drugs and pain score in the postoperative period. 100 patients in each treatment arm planned.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Irrigation with saline solution | Active Comparator | during abdominal hysterectomy after vaginal cuff closure abdominal saline irrigation will be done |
|
| control | No Intervention | routine abdominal hysterectomy will be performed and no abdominal saline irrigation |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Irrigation with Saline Solution | Drug | During hysterectomy after vaginal cuff closure 500-1000 mL saline irrigation will be done. |
|
| Measure | Description | Time Frame |
|---|---|---|
| postoperative infectious morbidities | vaginal cuff infection diagnosed with vagen cuff culture | 10 day after hysterectomy operation |
| Measure | Description | Time Frame |
|---|---|---|
| gastrointestinal outcomes: nausea by questionnaire | nausea by questionnaire | postoperative first day |
| gastrointestinal outcome: vomiting by questionnaire | vomiting by questionnaire |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kanuni Sultan Suleyman Training and research hospital | Recruiting | Istanbul | Turkey (Türkiye) |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D007507 | Therapeutic Irrigation |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D006875 | Hydrotherapy |
| D026741 | Physical Therapy Modalities |
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| postoperative first day |
| D008919 |
| Investigative Techniques |
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |