ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis | NCT07712835

NCT07712835

Overview

NCT ID: NCT07712835
Lead Sponsor: Children's Mercy Hospital Kansas CityOTHER
Official Title: ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
Brief Summary: This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant on Extracorporeal membrane oxygenation (ECMO). In a small multicenter cohort, the comparative analysis evaluated survival outcomes in this population with respiratory failure in the presence and absence of ECMO. Children's Mercy Kansas City served as the ECMO cohort; Cincinnati Children's Hospital Medical Center served as the matched non-ECMO cohort.
Conditions: ECMO Outcomes
Respiratory Failure (Pediatric Patients)

Status and Timeline

Status: Completed
Last Update Posted: Jul 20, 2026Actual
Start Date: Feb 2015Actual
Primary Completion Date: Dec 2024Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Child (0-17)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Less than 18 years old

Admitted to the PICU for respiratory failure (2015-2023)

Underlying oncologic diagnosis and/or hematopoietic stem cell transplant

Mechanical ventilation

Study Plan

Study Type: Observational
Phase: No data available
Enrollment: 22Actual
Primary Purpose: No data available
Allocation: No data available
Interventional Model: No data available
Masking: No data available

Contacts and Locations

Central Contacts: No data available
Locations: No data available

Similar Studies

Participant Group/Arms

ECMO Cohort

Eleven patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant received Extracorporeal membrane oxygenation (ECMO) as a rescue therapy for respiratory failure. Children's Mercy Hospital served as the ECMO cohort.

Other: Extracorporeal membrane oxygenation (ECMO)

Non-ECMO Cohort

Eleven patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant received conventional therapies for management of respiratory failure. Cincinnati Children's Hospital Medical Center served as the non-ECMO cohort.