This study aims to evaluate the efficacy of ivermectin in the treatment of plane warts( flat warts). patients diagnosed with plane warts will be included to assess the clearance ratre of the lesions.

Inclusion Criteria: • Clinical and dermoscopic diagnosis of the plane warts.

• No prior treatment for warts in the last 4 weeks.
• Patients of both sex (male - female)
• Age more than 5 years or weight more than 15 kg.

Exclusion Criteria:

• • Patients with other types of warts (e.g., common, plantar, genital).

  • History of hypersensitivity or allergy to ivermectin or its components.
  • Patients who have received systemic immunosuppressive therapy within the last 3 months.
  • Presence of chronic skin conditions that may interfere with evaluation (e.g., eczema, psoriasis).
  • Patients with immunodeficiency disorders (e.g., HIV, organ transplant recipients).
  • Pregnant or lactating females.
  • Patients currently on systemic antiviral or immunomodulatory treatment.