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To conduct a multi-center, randomized, controlled clinical study aimed at formally evaluating the impact of different acupuncture methods on the success rate in patients with recurrent implantation failure
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| placebo acupuncture group | Placebo Comparator | nonpenetrating placebo needles |
|
| acupuncture group 1 | Experimental | indwelling intradermal needles |
|
| acupuncture group 2 | Experimental | combining fire needle and regular acupuncture |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo Group | Device | nonpenetrating placebo needles |
| |
| Measure | Description | Time Frame |
|---|---|---|
| clinical pregnancy | defined as ultrasonographic detection of an intrauterine gestational sac following embryo transfer | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| β-hCG-positive pregnancy | defined as serum β-hCG concentration >10 mIU/mL on day 14 post-transfer | 2 years |
| live birth | defined as the delivery of 1 or more living infants at greater than 20 weeks' gestation or birth weight of at least 400 g |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pu Zhou | Contact | +8602783662379 | tongjihlunli@163.com |
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| acupuncture group 1 |
| Device |
indwelling intradermal needles |
|
| acupuncture group 2 | Device | combining fire needle and regular acupuncture |
|
| 3 years |