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This study aims to evaluate the effectiveness of continuous phenylephrine infusion at 50 mcg/min in preventing shivering after spinal anesthesia in cesarean section.
This study was an open-label randomized clinical trial involving patients undergoing cesarean section under spinal anesthesia. Subjects were allocated into two groups: without phenylephrine and continuous phenylephrine infusion at 50 mcg/min. The primary outcome was the incidence of shivering during observation, assessed using the Crossley and Mahajan scale. Secondary outcomes included hypotension, ephedrine requirement, hemodynamic adverse events, and nausea vomiting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Phenylephrine group | Experimental | This group will be given an intervention of phenylephrine continous infusion at rate 50 mcg/min |
|
| Without Phenylephrine group | No Intervention | this group doesnt receive any intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Phenylephrine | Drug | giving phenylephrine continous infusion at rate 50 mcg/minutes intravenously after insertion of spinal anesthesia |
|
| Measure | Description | Time Frame |
|---|---|---|
| Shivering | incidence of shivering after spinal anestesia intraoperatively | after the moment of spinal anesthesia until end of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Hypotension | incidence of hypotension after spinal anesthesia, define as decreasing of more than 20% of blood pressure from baseline | after the moment of spinal anesthesia until end of surgery |
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Inclusion Criteria:
Exclusion Criteria:
because the partipant was pregnant woman
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| RSUP dr. Cipto Mangunkusumo | Jakarta Pusat | Jakarta Special Capital Region | 10430 | Indonesia |
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| ID | Term |
|---|---|
| D007022 | Hypotension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D010656 | Phenylephrine |
| ID | Term |
|---|---|
| D004983 | Ethanolamines |
| D000605 | Amino Alcohols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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| D000588 |
| Amines |