Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence multiple neurobiological pathways such as neurotrophic signaling, neurotransmitter regulation, oxidative balance, and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and modulated biomarkers related to the hypothalamic-pituitary-adrenal axis with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ginseng | Experimental | ginseng |
|
| Placebo | Placebo Comparator | strawberry gummy (2) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ginseng | Dietary Supplement | This study will test the efficacy of ginseng on health compared to placebo treatment. |
|
| Measure | Description | Time Frame |
|---|---|---|
| cognitive performance | Trail Making Test: measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) | 2 hours post ingestion |
| cognitive performance | Trail Making Test measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| stress | Perceived Stress Scale: higher scores indicate higher stress | 2 weeks |
| mental well being | Warwick-Edinburgh Mental Well-Being Scale: higher scores indicating greater positive mental wellbeing |
| Measure | Description | Time Frame |
|---|---|---|
| cognitive performance | Stroop test: measures attention span, reaction time, and ability to resist distractions | 2 hours post ingestion |
| cognitive performance | reaction time test: measured by the elapsed time between stimulus onset and an individual's response |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Carol Johnston | Contact | 6024963463 | carol.johnston@asu.edu |
| Name | Affiliation | Role |
|---|---|---|
| Carol Johnston | Arizona State University | Principal Investigator |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000092862 | Psychological Well-Being |
| ID | Term |
|---|---|
| D010549 | Personal Satisfaction |
| D001519 | Behavior |
Not provided
Not provided
| ID | Term |
|---|---|
| C000713447 | Asian ginseng |
Not provided
Not provided
Not provided
This study will assess both the acute effect and long-term effect of ginseng consumption on cognition and mental well-being.
Not provided
Not provided
Not provided
| Placebo | Dietary Supplement | This study will test the efficacy of ginseng on health compared to placebo treatment. |
|
| 2 weeks |
| 2 hours post ingestion |