Stress Relief Effect of Korean Red Ginseng

Effects of Korean Red Ginseng on Stress Relief and Cognitive and Mental Function Enhancement Using Neuroimaging: Double-Blind, Randomized, Placebo-Controlled Clinical Trial

The purpose of this study is to examine clinical and neuropsychiatric effects of Korean Red Ginseng and examine changes in brain structure, function and metabolites. A total of 60 healthy volunteers will be recruited and will be assigned to either Korean Red Ginseng group or placebo group. Individuals will be examined through clinical assessment, neuropsychological function tests and neuroimaging.

Inclusion Criteria:

• Ages between 18~65

Exclusion Criteria:

• Current or past medical history, medical illnesses that are detected during clinical and physical evaluations
• Current Axis 1 diagnosis or past history of schizophrenia, bipolar, or psychotic disorders assessed by SCID-IV
• Current diagnosis of substance abuse assessed by SCID-IV
• Taking or have taken psychiatric medication in the past 2 months
• Head trauma accompanied by loss of consciousness or seizure
• IQ 80 or below
• Planning pregnancy, currently pregnant, or breastfeeding
• Claustrophobia or other fMRI incompatible factors such as pace makers
• Taking drugs, including over the counter drugs