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To evaluate the changes that occur in the intraocular pressure after corneal refractive surgery either PRK , LASIK and femtosecond laser by using Corvis CT results and applanation tonometer
This study will be prospective study. 50 Patients who will undergo refractive surgery referred from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study . The patient will be randomly selected to do either LASIK, PRK or femtosecond laser LASIK
Patients who will undergo refractive surgery either PRK, LASIK or femtosecond laser with age between 19 and 35 years old , Myopia range from (-2.00 to -6.00 Diopter) and to maintain stability of the data we will use only the right eye of each patient will be included on the study
Kertoconus, Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study.
Age, sex, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest and cycloplegic refraction, Slit lamp biomicroscopy, fundus examination , Central corneal thickness (CCT) and average Keratometer (K) data will be collected
Intraocular pressure will be measured by by two methods : Corvis CT and applanation tonometer for each patient and will be recorded, all the data will be collected before the refractive surgery and one month after refractive surgery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Measuring intraocular pressure by using different techniques | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Corvis machine | Other | Measuring intraocular pressure by different methods and compare the results |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measuring intraocular pressure | Intraocular pressure will be measured by in mmHg and by two methods : Corvis CT and applanation tonometer for each patient and will be recorded | -The data collected will be before that laser surgery and one month after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dina Tadros, Ass Professor of Ophthalmology | Contact | +201224093354 | dina.tadros@med.tanta.edu.eg |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tanta Univeristy Hospital | Tanta | 31515 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | 1. Bailey MD, Zadnik K (2007) Outcomes of LASIK for myopia with FDA-approved lasers. Cornea 26(3):246-254 2. Sridhar MS, Rao SK, Vajpayee RB, Aasuri MK, Hannush S, Sinha R (2002) Complications of laser-in situ-ker- atomileusis. Indian J Ophthalmol 50(4):265-282 3. Mohammadi SF, Nabovati P, Mirzajani A, Ashrafi E, Vakilian B (2015) Risk factors of regression and under- correction in photorefractive keratectomy: a case-control study. Int J Ophthalmol 18;8(5): 933-937 4. Diakonis VF, Kankariya VP, Kymionis GD, Kounis G, Kontadakis G, Gkenos E, Grentzelos MA, Hajithanasis G, Yoo SH, Pallikaris IG (2014) Long term followup of pho- torefractive keratectomy with adjuvant use of mitomycin C. J Ophthalmol 2014:821920 5- dos Santos AM, Torricelli AA, Marino GK, Garcia R, Netto MV, Bechara SJ, Wilson SE. Femtosecond Laser-Assisted LASIK Flap Complications. J Refract Surg. 2016 Jan;32(1):52-9 6- Wang LK, Tian L and Zheng YP. Determining in vivo elasticity and viscosity with dynamic Scheimpflug imaging analysis in keratoconic and healthy eyes. J Biophotonics, 2016; 9: 454-463. 7.ConsejoA,MelcerT,RozemaJJ.Introductiontomachinelearningforophthalmologists.SeminOphthalmol.2019;34(1):19 _41. |
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Results after statistical analysis will be shared in the manuscript
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol: Ethical committee approval. | Dec 4, 2025 | Mar 22, 2026 | Prot_000.pdf |
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