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In the study, The Investigators will compare the participates' corneal biomechanical properties including:
Deformation Amplitude ratio (Da Ratio) Integrated Radius (IR) Stress strain index (SSI)
All measurements will be taken before and after 3 months of LVC.
Each Participant will undergo preoperative pentacam and corvis scan for his eyes and the 3 months post operative.
The participants are divided into 3 groups, one who underwent LASIK, one PRK and one Femto LASIK.
Collected data will before and after surgery will be compared in each arm and then the 3 arms will be compared together.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laser In situ Keratomileusis (LASIK) | Active Comparator | Measurement of the deformation amplitude ratio, integrated radius and stress strain index as corneal biomechanical indices in refractive patients before and after LASIK |
|
| Femto-second assisted LASIK (FS-LASIK) | Active Comparator | Measurement of the deformation amplitude ratio, integrated radius and stress strain index as corneal biomechanical indices in refractive patients before and after Femto LASIK |
|
| Photorefractive Keratectomy (PRK) | Active Comparator | Measurement of the deformation amplitude ratio, integrated radius and stress strain index as corneal biomechanical indices in refractive patients before and after PRK |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CORVIS | Diagnostic Test | Measurement of the DA ratio, IR and SSI before and after for patients under gone LASIK, femto LASIK and PRK using the CORVIS device. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of the changes in DA ratio, integrated radius and SSI before and after LVC | Comparison between in DA ratio (DA ratio) in patients undergoing LASIK, Femto LASIK and PRK. Comparison between changes in integrated Radius (IR) in patients undergoing LASIK, Femto LASIK and PRK. Comparison between changes in Stress strain index (SSI) in patients undergoing LASIK, Femto LASIK and PRK. Each indices will be compared before and after the Laser vision correction (LVC) procedure and the indices are not to be compared to each other to have have a fixed unit measure. I reviewed your comment and I dont see any conflicts, to clarify how multiple measurements will be aggregated to arrive at one reported value again I am going to measure each index and compare it with "itself' before and after 3 different LVC. | 3-6 months post operative |
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Inclusion Criteria:
• Age range 18 - 40 years.
Exclusion Criteria:
• Patients with any other coexisting corneal diseases.
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| Name | Affiliation | Role |
|---|---|---|
| Mohamed Hosny | Cairo University | Principal Investigator |
| Mohamed Anis | Cairo University | Study Director |
| Wessam Salem | Cairo University | Study Chair |
| Mohamed ELnaggar | Research institute of Ophthalmology | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Cairo | Egypt |
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