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To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.
This study will be prospective study. 50 Patients will be included who will undergo corneal cross linking from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study .
Patient with age 19 till 35 years old will be included
Patient with Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study
All patient will undergo full ophthalmological examination. including best corrected visual acuity, degree of myopia , average kertometry and intraocular pressure will be measured before and after cross linkage with three different techniques including Shiotz tonometry, appalanation tonometry and CORVIS machine
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Measuring the intraocular pressure after cross linking | Other | Measuring the intraocular pressure by using different techniques after corneal cross linking |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Corvis Machine | Device | Measuring the intraocular pressure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intraocular pressure will be measured by using Corvis CT before cross linking and one month after cross linking | Recording the intraocular pressure | Through the end of the study in approximately one year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tamer Ibrahim, Ass professor of ophthalmology | Contact | +201001243049 | dinasabry71@gmail.com |
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The statistical analysis results will be shared through the manuscript
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol: Ethical approval for the study | Feb 26, 2026 | May 9, 2026 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
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