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This study investigates the effect of different dressings on skin pH when applied to a simulated skin fold environment.
This study evaluates the impact of various dressings on skin pH when applied to a simulated skin fold environment. To replicate the occlusive conditions commonly found in skin folds, a non-breathable film will be placed over the dressings, maintaining occlusion for approximately 24 hours.
Skin pH measurements will be taken during two separate visits: once before dressing application and again after approximately 24 hours of wear time. Both measurements will be conducted on the same location on the forearms of healthy participants. The goal is to investigate how different dressings influence skin pH under occlusive conditions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dressings | Experimental | Every participant will use all different dressing used in the trial. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dressings | Device | Sorbact® Ribbon, Sorbact® Compress and InterDry® |
|
| Measure | Description | Time Frame |
|---|---|---|
| Difference in skin pH | Difference in skin pH between the simulated skin fold and the area under Sorbact® Compress, measured after approximately 24 hours of wear time | 24 hours of wear time |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in skin pH | Difference in skin pH between the simulated skin fold and the area under Sorbact® Compress, | 24 hour of wear time |
| Difference in skin pH | Difference in skin pH between the simulated skin fold and the area under InterDry®, |
| Measure | Description | Time Frame |
|---|---|---|
| Differences in skin pH between the different dressings | Differences in skin pH measured under Sorbact® Ribbon, Sorbact® Compress and InterDry®. | 24 hours of wear time |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fana Hunegnaw | Contact | +46761361512 | fana.hunegnaw@essity.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Essity Study site | Recruiting | Mölndal | Sweden |
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| ID | Term |
|---|---|
| D001458 | Bandages |
| ID | Term |
|---|---|
| D004864 | Equipment and Supplies |
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| 24 hours of wear time |
| Change in skin hydration under occlusion from baseline | Change in skin hydration from baseline to after wear time, measured in the simulated skinfold under occlusion using a moisture meter | 24 hours of wear time |