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People with Parkinson's disease (PD) may have difficulty stopping or changing their movements, especially when walking around obstacles.
The goal of this observational study is to learn if a specific cognitive function, called inhibitory control (the ability to stop or control actions) is associated with gait adaptability in people with Parkinson's disease. Gait adaptability means the ability to adjust how a person walks in response to changes in the environment, such as stepping over obstacles.
The main questions the study aims to answer are:
Participants take part in one study visit. During this visit, participants complete simple thinking tests, have their brain activity recorded using EEG, and perform walking tasks that include stepping over obstacles.
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| Measure | Description | Time Frame |
|---|---|---|
| Event-related potential - N2 | Measure event-related potential through electroencephalography during the Go/No-go test | 1 day |
| Event-related potential - P300 | Measure event-related potential through electroencephalography during the Go/No-go test | 1 day |
| Stroop color and word test | Record numbers of corrected color words which the subject responds within 45 sec | 1 day |
| Step width | Using the GAITRite system to measure step width | 1 day |
| Stride length/Step length | Using the GAITRite system to measure stride length and step length during obstacle crossing | 1 day |
| Single support time | Using the GAITRite system to measure single support time during obstacle crossing | 1 day |
| Gait speed | Gait speed during obstacle crossing was measured using the GAITRite system. Continuous obstacle-crossing walking performance was assessed using the GaitUp system. | 1 day |
| Stride length | Using the GaitUp system to measure stride length during continuous obstacle-crossing walking. |
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Inclusion Criteria:
Exclusion Criteria:
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Community
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yea-Ru Yang, PhD | Contact | +886228267279 | yryang@nycu.edu.tw |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Yang Ming Chiao Tung University | Taipei | Taiwan |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| 1 day |
| Swing phase | Using the GaitUp system to measure swing phase during continuous obstacle-crossing walking. | 1 day |
| Swing width | Using the GaitUp system to measure swing width during continuous obstacle-crossing walking. | 1 day |
| Four Square Step Test | The Four Square Step Test is a test used to assess the ability to step over objects and measures the time in seconds to navigate all four squares. | 1 day |
| National Yang Ming Chiao Tung University | Taipei | Taiwan |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |