Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PD | Patients with Parkinson's disease |
| |
| Control | Healthy volunteers |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Walking test | Other | Walk with and without a metronome |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Stride cadence | Time between two consecutive heel strikes. Units are seconds. | Measured during the entire experiment (an average of 4.5 years) |
| Stride amplitude | Distance between two consecutive heel strikes. Units are meters. | Measured during the entire experiment (an average of 4.5 years) |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
One group of volunteers with previous diagnosis of Parkinson disease and one group of age and sex matched healthy volunteers.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| André Mouraux, PhD | Contact | +32 2 764 54 47 | andre.mouraux@uclouvain.be | |
| Frederic Crevecoeur | Contact | frederic.crevecoeur@uclouvain.be |
| Name | Affiliation | Role |
|---|---|---|
| Frederic Crevecoeur | Université Catholique de Louvain | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Université catholique de Louvain | Recruiting | Louvain-la-Neuve | 1348 | Belgium |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| Disease assessement |
| Other |
Disease stage assessed by a doctor |
|
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |