Cognitive-motor Training in Parkinson Disease

Cognitive-motor Training on Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson Disease

Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions. Stepping-based cognitive-motor training has been shown to improve cognitive functions, balance, and gait performance in older adults. However, there is insufficient research evidence on the impact and correlation of this training mode on the walking ability, executive functions, and brain activity changes in people with PD. Therefore, this study is designed to investigate the effects of stepping-based cognitive-motor training on the walking ability, executive functions, and brain activity in people with PD.

Inclusion Criteria:

• Diagnoses of idiopathic Parkinson disease
• Stable dopaminergic medicine ≥ 2 weeks
• Able to walk 10 meters without aid
• Mini-Mental Status Examination ≥ 24 points
• No uncorrected visual or auditory disorders
• Education at least junior high school
• No other disease may affect balance

Exclusion Criteria:

• Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
• History of brain surgery (e.g. deep brain stimulation)