Causation And Prognosis Analyses of Coronary Artery Disea... | NCT07480512

Studies
Causation And Prognosis Analyses of Coronary Artery Diseases: A Longitudinal Cohort Study

NCT07480512

Sponsor

Sun Yat-sen University

Status

Recruiting

Last Update Posted

Mar 18, 2026Actual

Enrollment

30,000Estimated

Phase

Not provided

Conditions

Coronary Artery Disease

Interventions

Not provided

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Mar 2026

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 1, 2013Actual

Primary Completion Date

Dec 31, 2032Estimated

Completion Date

Dec 31, 2032Estimated

First Submitted Date

Mar 13, 2026

First Submission Date that Met QC Criteria

Mar 13, 2026

First Posted Date

Mar 18, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 13, 2026

Last Update Posted Date

Mar 18, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This study is a single-center, historical prospective cohort study including patients diagnosed with coronary artery diseases, including stable angina pectoris, unstable angina pectoris, non-ST-segment elevation myocardial infarction, ST-segment elevation myocardial infarction, latent coronary artery diseases and ischemic cardiomyopathy. The primary outcome of the study is all-cause and cardiovascular mortality. We aim to investigate associations of established or suspected cardiovascular risk factors and the outcome in population with coronary artery dieseases in this real-world cohort.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

30,000Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
All-cause mortality	Death due to any cause after enrollment	Through study completion, an average of 5 years
Cardiovascular mortality	Death due to cardiovascular causes	Through study completion, an average of 5 years]

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Patients over 18 years old;
Patients with clinical diagnosis of coronary artery diseases, including stable angina pectoris, unstable angina pectoris, non-ST-segment elevation myocardial infarction, ST-segment elevation myocardial infarction, latent coronary artery diseases and ischemic cardiomyopathy.

Exclusion Criteria:

Patients unable to provide informed consent.

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Adult patients diagnosed with coronary artery diseases during hospitalization.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Xiaodong Zhuang, Professor	Contact	+8613760755035		zhuangxd3@mail.sysu.edu.cn

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
The First Affiliated Hospital, Sun Yat-sen Univerity	Recruiting	Guangzhou	Guangdong		China

Condition Browse Module

MeSH Terms

ID	Term
D003324	Coronary Artery Disease

Ancestor Terms

ID	Term
D003327	Coronary Disease
D017202	Myocardial Ischemia
D006331	Heart Diseases
D002318	Cardiovascular Diseases

Browse Leaves

Not provided

Browse Branches

Not provided