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This study is a prospective, single center cohort study that primarily registers the clinical characteristics, outcomes, and influencing factors of patients with different types of cardiovascular diseases. Evaluate multiple examination indicators of patients at baseline, 1 year and longer, and follow up on the incidence of major cardiovascular and cerebrovascular adverse events, heart failure readmission, death, and other endpoint events.
This study is a prospective, single center cohort study that primarily registers the clinical characteristics, outcomes, and influencing factors of patients with different types of cardiovascular diseases. Mainly including coronary heart disease, cardiomyopathy, hypertension, heart failure and other diseases, multiple examination indicators are evaluated for patients at baseline, 1 year and longer periods of time. The primary endpoints for coronary heart disease are all-cause mortality, cardiogenic death, non fatal myocardial infarction, hospitalization for heart failure, and major cardiovascular adverse events. The primary endpoints for cardiomyopathy are all-cause mortality, cardiogenic death, hospitalization for heart failure, and major cardiovascular adverse events. The primary endpoints for hypertension are stroke, all-cause mortality, cardiogenic death, hospitalization for heart failure, and major cardiovascular and cerebrovascular adverse events. The primary endpoints for heart failure are all-cause mortality, cardiogenic death, readmission for heart failure, and major cardiovascular adverse events.
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| Measure | Description | Time Frame |
|---|---|---|
| All cause death | Death caused by various reasons. | 1 year. |
| Cardiac death | Death caused by cardiac reasons. | 1 year. |
| Main adverse cardiovascular events(MACE) | The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, and cardiac death. | 1 year. |
| Heart failure | Heart failure (HF) is defined according to the diagnostic criteria for HF. Briefly, HF was defined as typical signs and symptoms of HF (NYHA class III or IV), as well as a history of myocardial infarct (MI) or with advanced coronary artery disease including severe 3-vessel disease and chronic total occlusion or other Organic heart disease. | 1 year. |
| Stroke | Stroke was defined as a sudden onset of vertigo, numbness, aphasia, or dysarthria caused by cerebrovascular disease, including hemorrhage, embolism, thrombosis, or aneurysm rupture, and persisting for > 24 hours | 1 year. |
| Measure | Description | Time Frame |
|---|---|---|
| Main adverse cardiovascular and cerebrovascular events(MACCE) | The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, cardiac death, and stroke. | 1 year. |
| Main adverse cardiovascular and cerebrovascular events(MACCE) |
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Inclusion Criteria:
Exclusion Criteria:
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The study population mainly includes patients with different types of cardiovascular diseases. Mainly including coronary heart disease, cardiomyopathy, hypertension, heart failure and other diseases.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ying-Ying Zheng, PhD | Contact | +8615214804944 | zhengying527@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Xiang Xie, Prof | Xinjiang Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Xinjiang Medicial University | Recruiting | Ürümqi | Xinjiang | 830000 | China |
Share the study protocol 6 months after the completion of the study.
6 months after study completion.
Sharing with scientific researchers.
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
| D006333 | Heart Failure |
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D001161 | Arteriosclerosis |
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Collect 5ml of fasting blood and store at -80 ℃.
The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, cardiac death, and stroke. |
| 3 years. |
| All cause death | Death caused by various reasons. | 3 years. |
| Cardiac death | Death caused by cardiac reasons. | 3 years. |
| Main adverse cardiovascular events(MACE) | The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, and cardiac death. | 3 years. |
| Heart failure | Heart failure (HF) is defined according to the diagnostic criteria for HF. Briefly, HF was defined as typical signs and symptoms of HF (NYHA class III or IV), as well as a history of myocardial infarct (MI) or with advanced coronary artery disease including severe 3-vessel disease and chronic total occlusion or other Organic heart disease. | 3 years. |
| Stroke | Stroke was defined as a sudden onset of vertigo, numbness, aphasia, or dysarthria caused by cerebrovascular disease, including hemorrhage, embolism, thrombosis, or aneurysm rupture, and persisting for > 24 hours | 3 years. |
| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |