Physiological and Biochemical Responses to Blood Flow Restriction Training

The Effects of Training History on Physiological and Biochemical Responses in Blood Flow Restriction Strength Training

This study is designed to examine the short-term and long-term effects of blood flow restriction exercise training on physiological and biochemical markers in individuals who are new to strength training and in experienced athletes training at different load levels. This exercise method involves placing a special inflatable cuff around the upper part of the thigh. The cuff partially limits blood flow to the area, which helps the muscles work more effectively during exercise. The cuff will be applied only to the individual's dominant leg (the leg you use more often in daily activities), but all exercises will be performed using both legs. The exercise program will last for a total of six weeks and will be carried out twice per week. The pressure applied by the cuff will be individually adjusted based on each participant's physical characteristics to ensure safety and comfort. The study will include a total of 30 healthy participants aged between 18 and 40 years. Participants will be divided into two groups: individuals who have recently started strength training and experienced athletes with different levels of training experience.

Inclusion Criteria:

• Voluntary participation of healthy adults
• Age between 18 and 40 years
• No history of orthopedic pathology or current symptoms affecting the lower extremities
• For individuals with prior training experience: engagement in strength training at least two days per week for the past year across different sports disciplines
• For individuals new to strength training: no regular participation in strength training within the past six months

Exclusion Criteria:

• History of hypertension, cardiovascular diseases, peripheral vascular diseases, deep vein thrombosis, neurological disorders, obesity, or a diagnosis of diabetes
• Current or previous diagnosis of cancer
• Individuals who do not consent to participate in the study