Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study

Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study

This study will refine and pilot test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention in a single-arm pilot trial. The study will test the hypothesis that the Peer-led Dynamic Choice HIV Prevention intervention will be feasible and increase biomedical HIV prevention coverage in the 6 months after receipt of the Peer-led DCP intervention compared to the standard of care in the 6 months prior to intervention implementation.

The overall goal of this study is to refine and pilot test a Peer-led Dynamic Choice HIV Prevention intervention tailored to women at elevated HIV risk in southwestern Uganda. We will conduct a single-arm pilot trial of the intervention enrolling approximately 60 women to assess the feasibility, acceptability, and preliminary effectiveness of the Peer-led Dynamic Choice Prevention intervention.

Inclusion Criteria:

1. Age >=18 years or mature or mature minor >=15 years;
2. Female sex at birth;
3. HIV negative by country-standard testing algorithm
4. Elevated risk of HIV exposure, defined as at least 1 of the following: a) eligible for PrEP based on Uganda Ministry of Health Guidelines; b) exchange of sex for goods or money in last 6 months; or c) work in bar or guesthouse

Exclusion Criteria:

• Contraindication to country-recommended PrEP regimen per national guidelines
• Participation in another HIV prevention study