Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Randomized Trial

Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Randomized Trial

This Hybrid Type 1 cluster randomized trial will test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention compared to standard of care.

This study will test a Peer-led Dynamic Choice HIV Prevention intervention tailored to women at elevated risk of HIV exposure in Western and South-Central Uganda. We will conduct a cluster randomized trial to test the effectiveness and implementation outcomes of a Peer-led Dynamic Choice HIV Prevention intervention for women.

Inclusion Criteria:

1. Age >=15 years (with parent/guardian consent required for age 15 to <18 years)
2. Female sex at birth;
3. HIV negative by country-standard testing algorithm;
4. Elevated risk of HIV exposure, defined as at least 1 of the following: a) eligible for PrEP/PEP based on Uganda Ministry of Health Guidelines or b) work in bar or guesthouse

Exclusion Criteria:

1. Contraindication to recommended PrEP/PEP regimen per Ministry of Health guidelines
2. Participation in another HIV prevention study
3. Aged 15 to <18 years with no parent or guardian to provide consent