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The primary objective of this observational study is to evaluate whether magnetocardiography (MCG) findings more accurately predict clinical outcomes in patients with acquired Long QT syndrome compared to ECG. The secondary objective is to assess differences in QT interval length between MCG and ECG. The primary safety objective is to characterize the safety profile of the CardiAQ MCG device.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects diagnosed with atrial fibrillation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnetocardiography | Diagnostic Test | MCG is a non-invasive, radiation-free imaging technique that detects the magnetic field generated by the electrical activity of the heart. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of successful dofetilide loading using Magnetocardiography | Dofetilide loading is considered successful if the following conditions are met:
| Baseline |
| Number of successful dofetilide loading using Electrocardiogram | Dofetilide loading is considered successful if the following conditions are met:
| Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Magnetocardiography - QT interval length | QT interval length is a measurement from the start of the Q wave to the end of the T wave. This will be measured in seconds. | Baseline |
| Electrocardiogram - QT interval length |
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Inclusion Criteria
Exclusion Criteria
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Study candidates may be identified and recruited in one of the following ways:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Patsy Caceres Figueroa | Contact | 507-266-3054 | caceresfigueroa.patsy@mayo.edu |
| Name | Affiliation | Role |
|---|---|---|
| Mohamad Alkhouli, M.D., M.B.A. | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| D053798 | Magnetocardiography |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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QT interval length is a measurement from the start of the Q wave to the end of the T wave. This will be measured in seconds.
| Baseline |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D004568 | Electrodiagnosis |
| D060306 | Magnetometry |
| D008919 | Investigative Techniques |