Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary objective of this observational study is to evaluate the utility of magnetocardiography (MCG) in diagnosing and monitoring disease progression in patients with amyloidosis, and to assess its effectiveness in comparison to other modalities, such as ECG.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with amyloidosis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SandboxAQ CardiAQ Magnetocardiography | Device | Magnetocardiography is a non-invasive, radiation-free imaging technique that detects the magnetic field generated by the electrical activity of the heart. |
| Measure | Description | Time Frame |
|---|---|---|
| Receiver Operating Characteristic (ROC) curve | Receiver Operating Characteristic (ROC) curve is used to compare true positive rate vs false positive rate. This will be used to determine the sensitivity, specificity, and overall effectiveness of MCG. | Baseline, 6 Months, 12 Months, 18 Months |
| Area Under the Curve (AUC) Magnetocardiography | Area Under the Curve (AUC) will be measured by mg*h/L. | Baseline, 6 Months, 12 Months, 18 Months |
| Area Under the Curve (AUC) Electrocardiogram | Area Under the Curve (AUC) will be measured by mg*h/L. | Baseline, 6 Months, 12 Months, 18 Months |
Not provided
Not provided
Inclusion Criteria
Exclusion Criteria
Not provided
Not provided
Not provided
Study candidates may be identified and recruited in one of the following ways:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andy Dang | Contact | 507-255-7752 | dang.phong@mayo.edu |
| Name | Affiliation | Role |
|---|---|---|
| Mohamad Alkhouli, M.D., M.B.A. | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic in Rochester | Recruiting | Rochester | Minnesota | 55905 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000686 | Amyloidosis |
| ID | Term |
|---|---|
| D057165 | Proteostasis Deficiencies |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided