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Participants will visit the study site twice in a fasting state. Participants asked to consume one of the two study products in a random order. Participants will consume one serving of the study product (T = 0 minutes). Study product intake should take place within 10 minutes (+/-5 minutes). Two blood samples will be taken at baseline and then at 14 timepoints after product intake. A follow up call will take place 7 (-3/+7) days after the final study visit.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yogurt first, Milk second | Active Comparator | All subjects will receive 2 study products on separate visits in a randomized order. |
|
| Milk first, Yogurt second | Active Comparator | All subjects will receive 2 study products on separate visits in a randomized order. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Full fat yogurt (fermented) | Other | Test |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incremental Area Under the Curve (iAUC ₀-₁₂₀) for Essential Amino Acids (EAA) in Blood After Ingestion of Product A or Product B | 2 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Incremental Area Under the Curve (iAUC ₀-₃₀₀) for Essential Amino Acids in Blood After Ingestion of Product A or Product B | 5 hours | |
| Incremental Area Under the Curve (iAUC ₀-₁₂₀) for Total Amino Acids in Blood After Ingestion of Product A or Product B |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Danone Global Research and Innovation Center | Contact | +31 30 2095 000 | register.clinicalresearchnutricia@danone.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| EB Medical Research | Recruiting | Almere Stad | Netherlands |
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A randomized controlled clinical study in healthy participants
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| Generic full fat pasteurized milk (non-fermented) | Other | Control |
|
| 2 hours |
| Incremental Area Under the Curve (iAUC ₀-₃₀₀) for Total Amino Acids in Blood After Ingestion of Product A or Product B | 5 hours |
| Maximum Concentration (Cmax) of Total Amino Acids and Essential Amino Acids in Blood After Ingestion of Product A or Product B | 5 hours |