Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Subjects will visit the study site twice in a fasting state. Subjects asked to consume one of the two study products in a random order. Subjects will consume one serving of the study product (T = 0 minutes). Study product intake should take place within 10 minutes (+/-5 minutes). Blood samples will be taken at baseline and then at various timepoints after product intake. A follow up call will take place 7 days after the final study visit.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoghurt | Experimental | Yoghurt test product (Commercially available) |
|
| Milk | Other | Commercially available product |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Milk | Other | Milk |
| |
| Yoghurt |
| Measure | Description | Time Frame |
|---|---|---|
| Total amino acid concentrations after ingestion of product A vs B in 16 healthy adults | To compare the relative amount (iAUC) total amino acids (TAA) appearing in the blood for the 4-hour period after the ingestion of product A versus B. | For 4 hours after product intake |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum concentration (Cmax) after ingestion of product A vs B in 16 healthy adults | To compare the maximum concentration (Cmax) and time to peak (Tmax) for total amino acids appearing in the blood for the 4-hour period after the ingestion of product A versus B in 16 healthy adults. | For 4 hours after product intake |
| Measure | Description | Time Frame |
|---|---|---|
| Time to peak of essential amino acids after ingestion of product A vs B in 16 healthy adults | To compare time to peak (Tmax), for essential amino acids (EAA) of product A versus product B. | For 4 hours after product intake |
| Relative amount of essential amino acid concentrations after consumption of product A vs. product B in 16 healthy adults. |
Inclusion Criteria:
Exclusion Criteria:
1 month prior to screening (except for incidental smoking of ≤ 3 cigarettes/ e-cigarettes/cigars/pipes per week on average in the last month prior to screening). 12. Average alcohol use of > 21 glasses per week for men or > 14 glasses per week for women (on average during the last 6 months prior to screening). 13. Drug or medicine abuse in opinion of the investigator. 14. Use of any nutritional supplements or additional protein supplements or nutritional support within 4 weeks prior to screening. 15. Known difficulties with placement of and/or blood drawings from a cannula. 16. Participation in any other clinical study with investigational or marketed products concomitantly or within four weeks before study visit
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| EB FlevoResearch | Almere Stad | Netherlands |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D008892 | Milk |
| D015014 | Yogurt |
| ID | Term |
|---|---|
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Other |
Yoghurt |
|
To compare the relative amount (iAUC) of essential amino acids (EAAs) appearing in the blood for the 4-hour period after the ingestion of product A versus product B. |
| For 4 hours after product intake |
| Maximum concentration (Cmax) of essential amino acids (EAAs) after product A vs. product B in 16 healthy adults. | To compare maximum concentration (Cmax) of essential amino acids (EAAs) appearing in the blood for the 4-hour period after the ingestion of product A versus product B. | For 4 hours after product intake |
| Time to peak of leucine product A vs. product B in 16 healthy adults | To compare time to peak (Tmax) for leucine of product A versus product B. | For 4 hours after product intake |
| Relative amount of leucine after product A vs. product B in 16 healthy adults. | To compare the relative amount (iAUC) of leucine appearing in the blood for the 4-hour period after the ingestion of product A versus product B. | For 4 hours after product intake |
| Maximum concentration of leucine after product A vs. product B in 16 healthy adults | To compare maximum concentration (Cmax) of leucine appearing in the blood for the 4-hour period after the ingestion of product A versus product B. | For 4 hours after product intake |
| D005502 |
| Food |
| D019602 | Food and Beverages |
| D043302 | Cultured Milk Products |
| D000074421 | Fermented Foods |