Synthetic THC And Blood Pressure

Effects Of Cannabis Products On Blood Pressure Control

To investigate the effects of Dronabinol use on blood pressure and neurovascular physiology

Inclusion Criteria

• Recreational occasional Cannabis use (Consuming THC less than 2 times a week)
• 21 - 40 years of age
• Biological male or female

Exclusion Criteria

• BMI > 35 kg/m2

• Diagnosed psychiatric disorders

• Hypotension

• History of seizures

• History of substance abuse or recreational drug use or positive urine drug screen

• History of uncontrolled disease including:

  • Cardiovascular
  • Pulmonary
  • Gastrointestinal
  • Pancreatic
  • Hepatic
  • Renal
  • Hematological
  • Endocrine (including Type I Diabetes)
  • Neurological
  • Urological
  • Sleep disorders

• Pregnant or breastfeeding

• Use of certain antimicrobial, chemotherapeutic, anticoagulant, hypoglycemic, anti-inflammatory, psychotropic, and antihistamine drugs

• Prescribed CYP2C9 and/or CYP3A4 inhibitors

• History of shift work or rotating shifts within 1 month