Tranexamic Acid : Nebulization vs IV Route for Hemoptysis

Tranexamic Acid : Nebulization vs IV Route for Hemoptysis

This study compares the effect of tranexamic acid on hemoptysis when given through the conventional IV route and Through nebulization.

The investigators are conducting a randomized controlled trial for the comparison of routes through which tranexamic acid can be given to control hemoptysis. The study participants will be divided into 2 groups randomly and 1 group will be assigned to use IV route while other will be assigned the nebulization route and the result variables include the time taken for complete control of hemoptysis and recurrence time. Another variable is the reduction in amout of blood in sputum after each intervention.

Inclusion Criteria:

1. Patients with mild to moderate hemoptysis < 600ml/ 24 hours of age 12 to 80 years and both genders.
2. Patients with hemoptysis due to infective pathology.
3. Patients with hemoptysis due to malignant pathology.

Exclusion Criteria:

1. Patients on antiplatelet therapy or aspirin
2. Hemoptysis after penetrating lung injury e.g. firearm injury
3. Patients with history of asthma