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| ID | Type | Description | Link |
|---|---|---|---|
| No. 23JRRA1064 | Other Grant/Funding Number | Science and Technology Department of Gansu Province |
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Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia. Furthermore, it explores the mediating role of gut microbiota in the association between the dietary inflammatory index and the risk of sarcopenia. The findings are expected to provide insights into the mechanisms through which dietary inflammation influences the development and progression of sarcopenia, and to offer a basis for dietary and nutritional interventions aimed at preventing or managing this condition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sarcopenia group and control group |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No Intervention: Observational Cohort | Other | No Intervention |
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| Measure | Description | Time Frame |
|---|---|---|
| The prevalence of sarcopenia | The diagnosis of sarcopenia is confirmed according to the AWGS 2019 criteria, which requires the assessment of muscle strength, physical performance, and muscle mass. | Through study completion, an average of 1 year |
| Change in absolute abundance of Faecalibacterium prausnitzii | 16S rRNA absolute quantification was used to detect the microbial composition of the fecal samples. | Through study completion, an average of 1 year |
| Dietary Characteristics | Dietary data were collected using a food frequency questionnaire (FFQ) to analyze dietary patterns and nutrient intake. | Through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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This community-based cross-sectional study enrolled permanent residents aged 60 years or older who had been living in the community for more than 5 years.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jianhua Ma Doctor of Medicine | Contact | 0086 18993157029 | majianhua@lzu.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lanzhou university | Recruiting | Lanzhou | Gansu | 730000 | China |
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| ID | Term |
|---|---|
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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Faecal and whole blood samples
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |