Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination.

Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination, a Pilot Study and Proof of Concept

Currently, standard brain MRI takes 20 to 25 minutes, but in the case of ischemic stroke, every minute counts to limit the extension of the necrotic core, with the possibility of recanalizing the occluded artery (intravenous thrombolysis and/or mechanical thrombectomy).

The recent concept of MRI "Fingerprint" (Magnetic Resonance Fingerprinting, MRF) allows the production of a rapid single sequence and the extraction of numerous parameters.

Demonstrating the feasibility and interpretability of multimodal MRI images acquired in MRF would make it possible to consider implementing and, ultimately, replacing conventional sequences, with the aim of shortening acute stroke management times, increasing the number of sequences acquired within a short timeframe (by increasing informativeness), and thus improving patients' short and long-term vital and functional prognosis.

Inclusion Criteria:

• Age > 18 years
• Subacute ischemic stroke patients (< 15 days after onset)
• Middle cerebral artery or anterior cerebral artery territory stroke
• Modified Rankin Scale (mRS) = 0-4

Exclusion Criteria:

* MRI contraindications