Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In the proposed study, the investigators assumed that Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Therapy (VRMCTOMT) will provide a better treatment effects than traditional virtual reality mirror therapy (VRMT) for the patients with unilateral stroke. The aim of the study is to examine the difference in the treatment effects among the combination of task-oriented training with either VRMCTOMT, or VRMT on the upper extremity function and brain activity of the stroke patients.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Virtual Reality Mirror Therapy Group | Active Comparator | 30 minutes of task-based Virtual Reality Mirror Therapy combined with 20 minutes of conventional task-oriented therapy. |
|
| Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy Group | Experimental | 30 minutes of Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy combined with 20 minutes of conventional task-oriented therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| task-oriented training | Other | Motor training targeted to goals that are relevant to the functional needs of the patient |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in the result of Fugl-Meyer assessment (FMA) for motor function of upper extremity test | Each item is rated on a three-point ordinal scale (2 points for the detail being performed completely, 1 point for the detail being performed partially, and 0 for the detail not being performed). The maximum motor performance score is 66 points for the upper extremity. | baseline, 9 weeks and 21 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the result of Modified Ashworth scale (MAS) | Muscle tone is defined by assess muscle tone by evaluating resistance to passive stretch, reflecting the level of spasticity, with scores ranging from 0 (no increase in tone) to 4 (rigidity in flexion or extension). | baseline, 9 weeks and 21 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the result of Box and blocks test | The score is the number of blocks carried from one box to the other in one minute. Higher values represent a better outcome. | baseline, 9 weeks and 21 weeks |
| Change in the result of Semmes-Weinstein monofilament (SWM) test |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hsiu-Yun Hsu, Ph.D | Contact | 886-6-2353535 | 2669 | hyhsu@mail.ncku.edu.tw |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cheng-Kung University Hospital | Recruiting | Tainan | Taiwan | 704 | Taiwan |
Not provided
Not provided
Not provided
Not provided
Not provided
| Virtual Reality Mirror Therapy | Other | Virtual Reality Mirror Therapy using goggle |
|
| Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy | Other | Virtual Reality-Based Generative Bimanual Cooperative Task-Oriented Mirror Therapy using goggle |
|
The Semmes-Weinstein monofilamenttest examines the cutaneous pressure threshold, range from 1.65-6.65. Higher values represent a worse outcome. |
| baseline, 9 weeks and 21 weeks |
| Change in the result of Motor Activity Log | Semi-structured interview examine how much and how well the subject uses their more-affected arm for 30 ADLs. Score range from 0-5. Higher values represent a better outcome. | baseline, 9 weeks and 21 weeks |
| functional Magnetic Resonance Imaging | a non-invasive neuroimaging technique that measures brain activity by detecting changes in blood oxygenation (BOLD signal). | baseline, 9 weeks |
| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided