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| Name | Class |
|---|---|
| The Craig H. Neilsen Foundation | OTHER |
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The purpose of this research is to determine the effects of food on cardiovascular and metabolic health in men with and without spinal cord injury (SCI).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low meal condition group | Experimental | Subjects will be in this group for up to 3 weeks. |
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| Moderate meal condition group | Experimental | Subjects will be in this group for up to 3 weeks. |
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| High meal condition group | Experimental | Subjects will be in this group for up to 3 weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low meal condition | Other | Participants will consume a standardized meal (500 grams) with a low nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Diet induced thermogenesis (DIT) | Diet-induced thermogenesis (DIT) will be measured using indirect calorimetry. A portable mask-based metabolic system, which will measure expired air to calculate dietary-induced thermogenesis defined as the energy expended above resting and the proportion of meal energy expended postprandially (postprandial kilocalorie (kcal) expended/total meal kcal) where a higher value means more energy is expended. | up to 3 weeks (collected during each of the intervention visits) |
| Hunger Series Visual Analog Scale | Satiety will be measured using the Hunger Series Visual Analog Scale (HSVAS), which assesses subjective appetite. Each scale is defined at 0 as "not at all hungry" and 100 as "totally/a lot/very hungry". A sum score will be calculated. | up to 3 weeks (collected during each of the intervention visits) |
| Post ad-libitum energy intake measured in grams | This value will be expressed as a ratio of energy consumed to energy requirements (energy intake/energy requirements x 100) and will be recorded in grams. | up to 3 weeks (collected during each of the intervention visits) |
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Inclusion Criteria:
SCI and Controls
SCI Only
Exclusion Criteria:
SCI and Controls
SCI Only
Male subjects
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guillermo Mederos | Contact | (305) 243-4518 | gxm1228@med.miami.edu | |
| Gary J Farkas, PhD | Contact | (305) 243-4518 | gjf50@med.miami.edu |
| Name | Affiliation | Role |
|---|---|---|
| Gary J Farkas, PhD | University of Miami | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Miami - Miami Project to Cure Paralysis | Recruiting | Miami | Florida | 33136 | United States |
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
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| Moderate meal condition | Other | Participants will consume a standardized meal (500 grams) with a moderate nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours. |
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| High meal condition | Other | Participants will consume a standardized meal (500 grams) with a high nutrient modification one time at one visit. Participants will attend one visit per week for 3 weeks. Each is visit separated by one week and each visit will take approximately 6 hours. |
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| Ad-libitum control condition | Other | The ad-libitum meal consists of 600-700 g of a standardized control meal one time at all visits. Participants will attend one visit per week for 3 weeks. Each visit is separated by one week and each visit will take approximately 6 hours. |
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| D014947 | Wounds and Injuries |