What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant insertion in the posterior region of mandible?

Effect of Vitamin D on Bone Regeneration .Vitamin D is known for its role in the skeletal system. Vit D deficiency is also widely researched for its effects on the healing of fractures, bone defects and osseointegration of implants. There are studies that investigated the effects of dietary supplementation with vitamin D to reduce vitamin D deficiency but increasing the serum level of this vitamin takes time therefore, an attempt has been made to combat the effect of vitamin D deficiency through topical application. up to the knowledge, upon search of literatures, there is not enough studies that correlate topical application of vitamin D with xenograft mixture as filling space material. this study is to Assess immediate implant with topical vitamin D and xenograft mixture clinically and Radiographically.

Inclusion Criteria:

• The American Society of Anesthesiologist (ASA) I , II
• Both Genders. 3- Patients having unrestorable tooth on the posterior mandibular region
• Age>20
• The patient who have complete their facial growth and teeth eruption
• No bone disease or lesion in propose implant site

Exclusion Criteria:

• Poor oral hygiene patients and/or patients
• Patients with active acute infection.
• Patients with bad oral habits.
• Pregnant or lactating women.
• Heavy smokers.
• Alcohol and drug addicts.
• Diabetes disease