Acute Effects of Instant Coffee in Capsule vs Beverage Form on Plasma Metabolites

The Acute Effect of Instant Coffee in Different Forms on Plasma Metabolites

This study is designed to evaluate the acute effect of consuming a cup of instant coffee on circulating metabolites and to evaluate whether ingestion of instant coffee in the form of a capsule has a similar effect on circulating metabolites as compared to the conventionally prepared beverage.

Inclusion Criteria: Healthy individuals aged 21-64 years old of Chinese ethnicity and are physically-abled, can participate in the research, and are able to understand English

Exclusion Criteria:

• Pregnant or breastfeeding
• Certain medications including Zanaflex, Sirasalud, Ketanest S, Spravato and Ephedrine Sulfate
• Any pre-existing medical conditions, depression, anxiety, caffeine/lactose intolerant, fear of needles and/or blood disorders, allergy to coffee or bovine capsules
• Existing dietary restrictions which makes them unable to consume non-halal certified bovine gelatin (the capsule encasing the coffee powder)
• Recent history of major surgical operations in the past year
• Past or current user of oral/systemic hormone treatment or therapies
• Taken antibiotics in the last 3 months
• Taking nutritional supplements (that contains coffee/tea-related compounds naturally found in other plants)
• Not willing to travel to the University for the study
• Unable to commit to completing both study visits