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This pilot study evaluates how progesterone levels change after hCG-triggered ovulation in modified natural cycles. Forty women preparing for frozen embryo transfer will have blood tests over 6 days to monitor hormone levels. The goal is to understand whether hCG affects the timing of the luteal phase and embryo implantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| hCG | Drug | Subcutaneous injection of 250 µg of recombinant hCG (Ovitrelle®) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Serum Progesterone Level on Day 3 After hCG Trigger | 3 Days After hCG Injection |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| NoƩmie RANISAVLJEVIC, Senior Lecturer - Hospital Pra | Contact | 04 67 33 64 81 | n-ranisavljevic@chu-montpellier.fr | |
| Anne CADENE, Project manager | Contact | 04.67.33.08.14 | a-cadene@chu-montpellier.fr |
| Name | Affiliation | Role |
|---|---|---|
| NoƩmie RANISAVLJEVIC, Investigator Coordinator | CHU de Montpellier | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| HƓpital Arnaud de Villeneuve | Recruiting | Montpellier | 34000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33829269 | Background | Mizrachi Y, Horowitz E, Ganer Herman H, Farhi J, Raziel A, Weissman A. Should women receive luteal support following natural cycle frozen embryo transfer? A systematic review and meta-analysis. Hum Reprod Update. 2021 Jun 22;27(4):643-650. doi: 10.1093/humupd/dmab011. | |
| 24602752 | Background | Lee VC, Li RH, Chai J, Yeung TW, Yeung WS, Ho PC, Ng EH. Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen-thawed embryo transfer in natural cycles. Fertil Steril. 2014 May;101(5):1288-93. doi: 10.1016/j.fertnstert.2014.01.040. Epub 2014 Mar 3. |
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