The Luteal Phase After GnRHa Trigger - a Proof of Concept Study

The Luteal Phase After GnRHa Trigger - a Proof of Concept Study

The purpose of this study is to investigate levels of progesterone in the luteal phase after various stimulations in the follicular phase and treatment with GnRH antagonist protocol followed by GnRHagonist as induction of ovulation.

The purpose of this study is to investigate levels of progesterone in the luteal phase after various stimulations in the follicular phase and treatment with GnRH antagonist protocol followed by GnRHagonist as induction of ovulation. Furthermore the aim is to explore whether the luteal phase can be supported with small daily boluses of hCG without the administration of exogenous P, while maintaining good reproductive outcome.

Inclusion Criteria:

• women from the age of 25 up to 40
• Serum-FSH and serum-LH levels under 12 IU/L
• Length of period between 25 and 34 days
• BMI between 18 and 30

Exclusion Criteria:

• less than 2 ovaries
• uterine abnormalities
• PCOS or UL-PCO (more than 11 follicles over 12 mm in 1 ovary