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Quantify the level of endocan in blood samples collected from patients with acute diverticulitis in the emergency department. Determine if endocan levels are correlated with the severity of diverticulitis according to the WSES classification. Assess whether patients requiring emergency surgical intervention have higher endocan values compared to others.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients with acute diverticulitis | Patients admitted to the emergency department with acute diverticulitis classified according to WSES statements. |
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| Measure | Description | Time Frame |
|---|---|---|
| Endocan serum level at admission | To evaluate the correlation between blood concentration of endocan and severity of diverticulitis | The serum of the patients enrolled inthe study will be collected within two hours from emergency room registation and tested for ENDOCAN |
| Measure | Description | Time Frame |
|---|---|---|
| Predictive value of endocan in determining which patients need emergency surgery | Concentration of endocan in grade 3-4 WSES compared to grade1-2 | Patients will undergo diverticulitis evaluations (per WSES criteria) within 3 hours of Emergency room admission and study enrollment |
| Prognostic value of endocan in determining the risk of recurrent diveritculitis |
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Inclusion Criteria:
Exclusion Criteria:
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Patients affected by acute diverticulitis in the emergency department
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emergency Department IRCCS San Raffaele | Milan | milano | 20132 | Italy |
All IPD that underlie results in a publication
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| ID | Term |
|---|---|
| D004238 | Diverticulitis |
| ID | Term |
|---|---|
| D000076385 | Diverticular Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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blood serum samples
Concentration of endocan in patient who develop a recurrence after 1 year follow-up |
| From discharge after definitive tretament till 12 months follow-up |