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The research aimed to improve surgical techniques and long-term outcomes by utilizing this advanced imaging technology to illuminate the structural abnormalities of the anterior segment in eyes with primary congenital glaucoma.
Primary congenital glaucoma (PCG) is a rare disease, but it is responsible for 2.5%-15% of all documented cases of pediatric blindness.
The main target of the treatment of pediatric glaucoma is to control the IOP surgically. However, medical treatment could be instituted as a temporary and/or adjunctive option to maximize Intraocular pressure (IOP) control. Initial goniotomy or trabeculotomy have been detected to have high success rates. Trabeculotomy has a comparable long-term success rate in most patients of PCG. The success rate of trabeculotomy is lower in advanced or late-presenting patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary congenital glaucoma group | Experimental | Infants with primary congenital glaucoma. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optical coherence tomography | Procedure | Infants underwent optical coherence tomography. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Central corneal thickness | Central corneal thickness was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). | 6 months post-procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Trabecular-iris angle | Trabecular-iris angle was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). | 6 months post-procedure |
| Iris thickness | Iris thickness was measured using handheld anterior segment optical coherence tomography (HH AS-OCT). |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Cairo | 12613 | Egypt |
The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
After the end of study for one year.
The data will be available upon a reasonable request from the corresponding author.
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| 6 months post-procedure |
| ID | Term |
|---|---|
| D006871 | Hydrophthalmos |
| ID | Term |
|---|---|
| D005124 | Eye Abnormalities |
| D005128 | Eye Diseases |
| D005902 | Glaucoma, Open-Angle |
| D005901 | Glaucoma |
| D009798 | Ocular Hypertension |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D007232 | Infant, Newborn, Diseases |
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| ID | Term |
|---|---|
| D041623 | Tomography, Optical Coherence |
| ID | Term |
|---|---|
| D041622 | Tomography, Optical |
| D061848 | Optical Imaging |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D014054 | Tomography |
| D008919 | Investigative Techniques |
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