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Optical coherence tomography (OCT) for retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) is done before and after cataract extraction in patients with or without primary open angle glaucoma (POAG)
The investigator's study includes two groups of patients, each consists of 25 eyes, group 1 (cataract group)includes patients who are planned for cataract extraction without any other preexisting retinal or optic nerve pathology that may affect the RNFL thickness, while group 2 (combined cataract and glaucoma group) includes patients who are diagnosed with POAG controlled on medical treatment with cataract and planned for cataract extraction only.
The OCT scans with complete ophthalmological examination are done before surgery and 6 weeks after uneventful cataract extraction (phacoemulsification with intraocular lens implantation)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cataract group | Group 1 includes patients who are planned for cataract extraction without any other preexisting retinal or optic nerve pathology that may affect the RNFL thickness. OCT (investigation) before and after cataract extraction |
| |
| Combined cataract and glaucoma group | Group 2 includes patients who are diagnosed with POAG controlled on medical treatment and have cataract and planned for cataract extraction only OCT is done before and after cataract extraction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oct scans | Diagnostic Test | Oct scans to assess thickness of RNFL and GCC before and after cataract extraction surgery in both groups |
|
| Measure | Description | Time Frame |
|---|---|---|
| RNFL and GCC thickness | Assessment of RNFL and GCC thickness change after cataract extraction | Oct scans before and 6 weeks after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Final best corrected visual acuity (BCVA) | Assessment of the final BCVA recorded according to the Snellen chart and converted to logMAR for statistical analysis | Six weeks after cataract surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Intraocular pressure (IOP) change and central foveal thickness (CFT) change | Assessment of the IOP and CFT change after cataract extraction | Six weeks after cataract surgery |
Inclusion Criteria:
• patients with cataract without any other concomitant retinal, optic nerve head pathology other than POAG are included in the study and divided onto two groups
Exclusion Criteria:
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Patients with cataract without any other concomitant retinal, optic nerve head pathology other than POAG are included in the study and divided into two groups Group 1 patients with cataract only Group 2 patients with cataract and POAG who are planned for cataract surgery only and controlled on medical treatment
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kasr Al-Ainy teaching hospital | Cairo | 11562 | Egypt |
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| ID | Term |
|---|---|
| D002386 | Cataract |
| D005902 | Glaucoma, Open-Angle |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
| D005901 | Glaucoma |
| D009798 | Ocular Hypertension |
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