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The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .
Hirsuitism refers to excessive terminal hairs in females, following a distribution pattern typically associated with male. It is associated with either increase response of hair follicles to androgen or either increase level of circulating androgens.The treatment options available are topical creams like eflornithine and laser treatments for hair removal. This study aims to conduct the comparison of a eflornithine cream and intense pulsed light laser versus eflornithine cream alone for the treatment of excessive facial hairs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GroupA | Experimental | This group is treated with combination of eflornithine cream and intense pulsed light for a period of three month. |
|
| Group B | Experimental | This group is treated with eflornithine cream twice daily only for a period of three month |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Eflornithine Topical | Drug | Eflornithine cream will be applied to the face of group B female patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of treatment | Efficacy of treatment is defined as complete clearance of excessive hairs assesed on the basis of 4- level scale ranging 0 to 3 after 3 months of administration of the treatment in both groups. Clear is grade 3 Marked improvement is grade2 Improved is grade1 No improvement is grade 0 | 3 months |
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Inclusion Criteria:
Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition
Exclusion Criteria:
Pregnant women Women with severe acne Women with immunodeficiency
All the female patients with excessive facial hairs were included in the study.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Umaima Nazar, MBBS | Contact | +923355869079 | +923355869079 | umaimanazar123@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Khyber Teaching Hospital | Recruiting | Peshawar | Kpk | 25000 | Pakistan | |
| Khyber Teaching Hospital |
Because the confedentiality of the patient would be breached.
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| Instense pulsed light | Radiation | Intense pulse light will be applied to the face of patient of Group A on areas having increase hair. Patient will be called for a followup every month for next session. |
|
| Eflornithine Topical | Drug | Eflornithine will be given to group A patient along with intense pulsed light and results will be compared to group B who recieved only Eflornithine cream |
|
| Recruiting |
| Peshawar |
| KPK |
| Pakistan |
|
| Khyber Teachinng Hospital | Recruiting | Peshawar | KPK | Pakistan |
| ID | Term |
|---|---|
| D006628 | Hirsutism |
| ID | Term |
|---|---|
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D014770 | Virilism |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D000518 | Eflornithine |
| ID | Term |
|---|---|
| D009952 | Ornithine |
| D024361 | Amino Acids, Basic |
| D000596 | Amino Acids |
| D000602 | Amino Acids, Peptides, and Proteins |
| D000599 | Amino Acids, Diamino |
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