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The purpose of this study is to compare the efficacy of the IPL system 650advance handpiece with the alexandrite laser for the purposes of female facial hair reduction
This is a randomised (splitface)controlled trial, comparing the use of the Intense Pulsed Light (IPL) system 650 advance handpiece against the Alexandrite Laser for the purposes of female facial hair reduction. Previous studies have shown that the alexandrite laser is superior to IPL in achieving hair reduction. A new handpiece (Lynton, Lumina 650 advance) available for the IPL system is designed to further optimise its use in removing female facial hair (particularly those hair colours previously unresponsive to treatment). This study will compare the alexandrite laser to the IPL system using the new handpiece. This may lead to improvements in the treatment of female patients with male pattern facial hair. Female patients referred to our facial hair reduction service will be recruited to this study. 1/2 their face will be treated with IPL and 1/2 with alexandrite laser. Each participant will receive 6 full treatments at approximately 6 weekly intervals. Participants will be asked to fill in a satisfaction questionnaire and have clinical photographs taken pre treatment and at 1 and 3months post final treatment. All treatments will be carried out in our dedicated laser suite at Glasgow Royal Infirmary.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IPL | Active Comparator | Half face treated with IPL |
|
| Alexandrite Laser | Active Comparator | Half face treated with Alexandrite Laser |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intense Pulsed Light (IPL) | Device | Half Face Treated with IPL |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in total Hair Count measurement at 1month post final treatment from baseline | Pre Treatment hair count assessed using videomicroscopy as baseline. Post final treatment hair counts will be measured again at 1month to assess if there has been a reduction in total hair count from pre-treatment | Baseline and 1 month |
| Change in total hair count at 3months post final treatment from baseline | Pre Treatment hair count assessed using videomicroscopy as baseline. Post final treatment hair counts will be measured again at 3months to assess if there has been a reduction in total hair count from pre-treatment | Baseline and 3months post final treatment |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Adam Gilmour, MBChB, MRCS (Ed) | NHS Greater Glasgow & Clyde | Principal Investigator |
| Iain Mackay, MBChb, MRCS, FRCS (plast) | NHS Greater Glasgow & Clyde | Study Chair |
| Vivek Sivarajan, MBChB, MRCS, MD, FRCS (Plas) | NHS Greater Glasgow & Clyde | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary | Glasgow | G4 0SF | United Kingdom |
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| ID | Term |
|---|---|
| D006628 | Hirsutism |
| ID | Term |
|---|---|
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D014770 | Virilism |
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| ID | Term |
|---|---|
| D062325 | Intense Pulsed Light Therapy |
| D053844 | Lasers, Solid-State |
| ID | Term |
|---|---|
| D010789 | Phototherapy |
| D013812 | Therapeutics |
| D007834 | Lasers |
| D055096 | Optical Devices |
| D004864 |
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| Alexandrite Laser |
| Device |
Half face treated with Alexandrite Laser |
|
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| Equipment and Supplies |
| D055618 | Radiation Equipment and Supplies |