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This study aimed to compare WHO treatment of acute watery diarrhea with or without probiotic (bacillus clausii) in term of mean duration of diarrhea in children
Available literature regarding the use of probiotics is not conclusive and contains controversy, and local data is also scarce. Therefore, this study was planned to further explore the use of probiotics to furnish the local data. If significantly less mean duration of diarrhea is noted in the probiotic group, it will help to add probiotic bacillus clausii in routine treatment regimen recommended by WHO and to decrease costs associated with prolonged treatment. However, if otherwise results will be noted it will help to rule out use of probiotic bacillus clausii in children with acute diarrhea to avoid its unnecessary use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotic group | Experimental | Patients received 2 billion spores of probiotic (Bacillus clausii) every 12 hours, contained in a small bottle along with standard treatment as per WHO guidelines. |
|
| No probiotic group | No Intervention | Patients received only standard treatment as per WHO guidelines. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic Bacillus Clausii | Drug | Patients were given 2 billion spores of probiotic (Bacillus clausii) every12 hours, contained in a small bottle. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stool frequency | A frequency of defecation of < 3 stools per day marked the effectiveness of the treatment. | 5 days |
| Consistency of stools | The treatment was considered effective if the consistency of stools became semi-solid. | 5 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Talha Hassan | Children Hospital, Lahore, Pakistan | Principal Investigator |
| Muhammad Zeeshan | Children Hospital, Lahore, Pakistan | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Children Hospital | Lahore | Punjab Province | 54000 | Pakistan |
Data can be shared on a reasonable request.
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