The current study was carried out to directly compare the effectiveness of zinc supplementation with ORS and Bacillus clausii versus zinc with ORS and Saccharomyces boulardii among the local pediatric population presenting with acute watery diarrhea.

The results and importance of effective treatment for acute watery diarrhea in pediatric patients vary throughout the world. Previously, very limited literature was available comparing the efficacy of Bacillus clausii and Saccharomyces boulardii in acute watery diarrhea, providing mixed results. The current study aims to directly compare the effectiveness of zinc supplementation with ORS and Bacillus clausii versus zinc with ORS and Saccharomyces boulardii.

Inclusion Criteria:

• Patients of either gender
• Aged 3 months to 5 years
• With acute watery diarrhea last less fewer than 14 days
• Presenting with mild to moderate dehydration

Exclusion Criteria:

• Patients with a history of blood or pus in their stools
• History of recent antibiotic or probiotic treatment
• Patients with immunodeficiency conditions, acute systemic illnesses, or chronic diarrhea
• Patients with hypersensitivity to Bacillus clausii or Saccharomyces boulardii

Data can be shared with other researchers on a reasonable request