Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this observational study is to determine the relationship of ROTEM point-of-care coagulation assay parameters with excessive bleeding and clinical outcomes in patients undergoing cardiac surgery at Toronto General Hospital. The main questions it aims to answer are: i) How well does viscoelastic testing (VET) predict the clinical outcome of excessive bleeding in cardiac surgery? ii) Which VET parameters have the greatest accuracy for identification of patients who will have excessive bleeding? iii) 3) What is the prognostic value of abnormal VET parameters with other clinical outcomes after cardiac surgery?
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cardiac surgery patients | Adult patients undergoing cardiac surgery on cardiopulmonary bypass at Toronto General Hospital |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention (observational study) | Other | This is an observational study. No intervention. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Excessive bleeding | Measured by the universal definition of perioperative bleeding (UDPB) scale | From the end of bypass to the end of postoperative day-1 (POD1) |
| Measure | Description | Time Frame |
|---|---|---|
| Transfusion rate | Incidence and amount of transfusion of allogeneic blood products and factor concentrates | 1) From time of entry to operating room (OR) to the end of post-operative day-1 (POD1) and post-operative day-7(POD7). 2) from end of cardiopulmonary bypass (CPB) to the end of post-operative day-1 (POD1) and post-operative day-7 (POD7) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
- Did not undergo viscoelastic testing during surgery
Not provided
Not provided
Not provided
Patients undergoing cardiac surgery with cardiopulmonary bypass at Toronto General Hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Keyvan Karkouti | Contact | 416-340-4800 | 8597 | keyvan.karkouti@uhn.ca |
| Deep Grewal | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Keyvan Karkouti | University Health Network, Toronto | Principal Investigator |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided
| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
Not provided
Not provided